发明名称 Derivatives of docosahexaenoylethanolamide and uses thereof
摘要 The invention provides derivatives of DEA which have increased potency and hydrolysis resistance as compared to DEA, and compositions thereof, as well as methods of using these derivatives to promote neurogenesis, neurite growth and/or length, and/or promote synaptogenesis.
申请公布号 US9422308(B2) 申请公布日期 2016.08.23
申请号 US201314387410 申请日期 2013.03.15
申请人 The United States of America, as represented by the Secretary, Department of Health and Human Services 发明人 Kim Hee-Yong;Marugan Juan Jose;Englund Erika E.;Patnaik Samarjit
分类号 C07D495/04;C07D213/40;C07D319/20;C07D205/04;C07C235/28;C07D309/04;C07D333/20;C07D235/14;C07C233/09;C07C233/13;C07C233/20;C07C233/23;C07C233/31;C07C233/38;C07C233/49;C07C255/29;C07D295/13;C07D295/135;C07D295/185;C07D307/52 主分类号 C07D495/04
代理机构 Leydig, Voit & Mayer, Ltd. 代理人 Leydig, Voit & Mayer, Ltd.
主权项 1. A compound having the formula: CH3CH2HC═CHCH2HC═CHCH2HC═CHCH2HC═CHCH2HC═CHCH2HC═CHCH2CH2CO—NR1R2, wherein the group NR1R2 is selected from:
地址 Washington DC US