| 发明名称 | 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as FAK/Pyk2 inhibitors | ||
| 摘要 | The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/or Pyk2 mediated disorder or disease. | ||
| 申请公布号 | US9428508(B2) | 申请公布日期 | 2016.08.30 |
| 申请号 | US201213978475 | 申请日期 | 2012.01.07 |
| 申请人 | Centaurus BioPharma Co., Ltd. | 发明人 | Xiao Dengming;Cheng Liang;Liu Xijie;Hu Yuandong;Xu Xinhe;Liu Zhihua;Zhang Lipeng;Wu Wei;Wang Shulong;Shen Yu;Li Gen;Wang Yin;Zhao Sheng;Li Chonglong;Tang Jia;Yu Honghao |
| 分类号 | C07D487/04;C07D413/12;A61K31/519;A61K31/5377;A61K31/541;A61K31/4523;A61P35/00;C07D401/12;C07D493/12;C07D417/12 | 主分类号 | C07D487/04 |
| 代理机构 | Leason Ellis LLP. | 代理人 | Leason Ellis LLP. |
| 主权项 | 1. A compound selected from: or a pharmaceutically acceptable salt, solvate, or tautomer thereof. | ||
| 地址 | Beijing CN | ||