(Nitrofuryl)pyrazoles, their synthesis and use, and compositions containing them

摘要

3-(5-Nitro-2-furyl)pyrazoles unsubstituted in the 5-position and 5-(5-nitro-2-furyl)pyrazoles unsubstituted in the 3-position are antimicrobials and disinfectants. The compounds are structurally represented by one of the formulae: <IMAGE> <IMAGE> (I) wherein A is -CHO, -CN, -COOH, a protected or derived aldehyde group or a protected or derived carboxylic acid group; B is 5-nitro-2-furyl; R1 is -H, substituted or unsubstituted hydrocarbyl (saturated or unsaturated; acyclic, alicyclic or aromatic; or araliphatic); substituted or unsubstituted (cycloaliphatic or aromatic) heterocyclic or acyl (carboxylic or carbonic acid); R2 is -H; and N IS A POSITIVE WHOLE NUMBER OF AT MOST 2.