发明名称 PROCESS FOR THE PREPARATION OF 16-OXYGENATED PROSTANOIC ACID DERIVATIVES
摘要 Title compds.(I; R1,R2,R3 = H, C1-7 alkyl; R4 = C1-7 al-kyl; R5 = H, alkyl, C1-7 alkanoyl; R6 = C2-4 alkyl, C5-7 cycloalkyl; X = carbonyl, hydroxymethylene; V = methylene, alkanoylxymethylene; Y = ethylene, vinylene; Y' = vinylene; Z = ethylene, vinylene) were prepd. by treating II with III(R5 = H, C1-7 alkyl, alkanoyl tetrahydrofuranyl; M = metal). These compds. inhibited gastric juice secretion, platelet aggregation and fertilization, and exhibited bronchodilative action.
申请公布号 KR800000715(B1) 申请公布日期 1980.07.23
申请号 KR19750000621 申请日期 1975.03.25
申请人 G D SEARLE & CO 发明人 COLLINS P;PAPPO R
分类号 (IPC1-7):C07C61/38 主分类号 (IPC1-7):C07C61/38
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