RECOMBINANT POLYPEPTIDE CYTOTOXINS FOR CANCER TREATMENT

摘要

Recombinant polypeptide cytotoxins are provided which comprise a cytokine or cytokine subunit or a single chain antibody subunit fused to a polypeptide toxin which suppress the proliferation of a population of mammalian cells by causing apoptotic cell death. The invention further provides a method which utilizes the disclosed recombinant polypeptide cytotoxins to systemically treat cancer patients.