发明名称 IBUPROFEN-ANTITUSSIVE COMBINATIONS
摘要 2107332 9217177 PCTABS00016 This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation and the relief of cough and cold symptoms in a mammalian organism, said composition comprising: (i) an analgesically and anti-inflammatory effective amount of (S)-ibuprofen, or a salt thereof, substantially free of (R)-ibuprofen; and (ii) an antitussively effective amount of at least one antitussive agent selected from codeine, hydrocodone, caramiphen, carbetapentane, or dextromethorphan, or a therapeutically active stereoisomer thereof substantially free of its other stereoisomers and optionally (iii) a therapeutically effective amount of at least one expectorant selected from guaicolsulfonate, guaifenesin, guaiacol, or terpin; or a pharmaceutically acceptable salt thereof.
申请公布号 CA2107332(A1) 申请公布日期 1992.10.02
申请号 CA19922107332 申请日期 1992.03.24
申请人 MERCK & CO., INC.;MCNEIL-PPC, INC. 发明人 SIMS, ROBERT T.;SLIVKA, WILLIAM
分类号 A61K31/085;A61K31/19;A61K31/215;A61K31/485;A61P11/10;A61P11/14;A61P25/04;(IPC1-7):A61K31/19 主分类号 A61K31/085
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