| 摘要 |
FIELD: organic chemistry, chelate compounds. SUBSTANCE: invention describes a water- -dissolved inclusion complex containing a compound of the formula (I) where R and R each means independently hydrogen atom, C<SB>1</SB>-C<SB>4</SB>-alkyl, -CO-(C<SB>1</SB>-C<SB>6</SB>-alkyl or -CO-Ar where Ar is optionally substituted phenyl; and R is taken from the group involving pyrrolidino-, hexamethyleneimino- an piperidine-group; or its salt and water-soluble cyclodextrin at concentration 10-50% (mass/volume). Also, invention describes pharmaceutical compositions for these inclusion complexes and methods of their using for inhibition of bone shrinkage and serum cholesterol content decrease in mammals. EFFECT: improved method of synthesis, enhanced curative effectiveness. 9 cl, 1 ex
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