METHOD OF TREATMENT OR PROPHYLAXIS OF MAMMALS AND HUMAN WITH VOMITING USING SOME QUINUCLIDINE, PIPERIDINE, AZANORBORNANE, ETHYLENEDIAMINE DERIVATIVES AND RELATED COMPOUNDS

摘要

FIELD: organic chemistry, pharmacology. SUBSTANCE: method involves treatment or prophylaxis of mammals with vomiting using the following compounds: (2S, 3S)-N-(5-tert. -butyl-2-methoxy- -phenyl)-methyl-2-diphenylmethyl-1-azadicyclo(2,2,2)octane-3- -amine, (2S,3S)-N-(5-isopropyl-2-methoxyphenyl)-methyl-2- -diphenylmethyl-1-azadicyclo(2,2,2)octane-3-amine and (2S, 3S)-2-phenyl-3-(2-methoxy-5-trifluoromethoxybenzyl)- -aminopiperidine. EFFECT: enhanced effectiveness of treatment. 3 cl, 24 dwg, 3 ex