发明名称 |
Calmodulin-based cell separation technique |
摘要 |
The invention provides a method for separating target cells from a plurality of cells which is based on a reversible high affinity interaction between two molecules. The method comprises: forming a target cell/cell binding reagent/first molecule/second molecule/solid support complex, wherein the cell binding reagent is specific for target cells present within a plurality of cells and wherein the first molecule reversibly binds to the second molecule; removing non-target cells of the plurality of cells not attached to the solid support; and reversing the first molecule binding to the second molecule, thereby releasing the target cells as separate cells from the plurality of cells.
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申请公布号 |
US5985658(A) |
申请公布日期 |
1999.11.16 |
申请号 |
US19970970363 |
申请日期 |
1997.11.14 |
申请人 |
HEALTH RESEARCH INCORPORATED |
发明人 |
COLINAS, ROBERT JAMES;WALSH, ANNE CATHERINE;LAWRENCE, DAVID A. |
分类号 |
C12N5/00;C12N5/06;G01N33/50;(IPC1-7):C12N5/00;C12N5/02;G01N33/53;G01N33/536 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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