发明名称 |
Methods of assessing HIV integrase inhibitor therapy |
摘要 |
The present invention relates to methods and products for the evaluation of HIV treatment. The methods are based on evaluating molecular events at the HIV integrase resulting in altered therapeutic efficacy of the investigated compounds. The methods rely on providing an integrase gene and evaluating either through genotyping or phenotyping the integrase gene. The present invention relates to the fields of diagnostics, drug screening, pharmacogenetics and drug development.
|
申请公布号 |
US7189505(B2) |
申请公布日期 |
2007.03.13 |
申请号 |
US20050203768 |
申请日期 |
2005.08.15 |
申请人 |
TIBOTEC BVBA |
发明人 |
VINGERHOETS JOHAN HENDRIKA JOZEF;MICHIELS LIEVE EMMA JAN;DIERYNCK INGE |
分类号 |
C12N15/10;A61K49/00;C12N15/49;C12N15/63;C12N15/867;C12Q1/68;C12Q1/70 |
主分类号 |
C12N15/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|