| 发明名称 |
TOLEROGENIC DENDRITIC CELLS TO TREAT INFLAMMATORY BOWEL DISEASE |
| 摘要 |
Methods are disclosed herein for treating or preventing an inflammatory bowel disease in a subject. These methods include administering to a subject an effective amount of tolerogenic dendritic cells, wherein the tolerogenic dendritic cells comprise at least one of an antisense compound specific for CD40, and antisense compound specific for CD80 and an antisense compound specific for CD86. |
| 申请公布号 |
US2016230174(A1) |
申请公布日期 |
2016.08.11 |
| 申请号 |
US201415025208 |
申请日期 |
2014.09.26 |
| 申请人 |
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
Giannoukakis Nick;Trucco Massimo M. |
| 分类号 |
C12N15/113;A61K45/06;A61K31/7088;A61K35/15 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating or preventing inflammatory bowel disease in a subject, comprising administering to the subject a therapeutically effective amount of a composition comprising an effective amount of tolerogenic dendritic cells, wherein the tolerogenic dendritic cells comprise at least one of an antisense compound specific for CD40, an antisense compound specific for CD80 and an antisense compound specific for CD86, thereby treating or preventing the inflammatory bowel disease in the subject. |
| 地址 |
Pittsburgh PA US |
