发明名称 Novel benzimidazole derivatives as kinase inhibitors
摘要 The present invention relates to derivatives of benzimidazoles of formula (I) as disclosed herein as well as pharmaceutical compositions comprising said derivatives. The derivates according to the present invention are serine/threonine and tyrosine kinase-inhibitors, particularly of PIM1-3-and DYRK1A-kinases and may particularly be used in the treatment of diseases linked to these kinases, such as e.g. leukemias, lymphomas, solid tumors and autoimmune disorders.
申请公布号 AU2013366513(B2) 申请公布日期 2016.09.01
申请号 AU20130366513 申请日期 2013.12.20
申请人 SELVITA S.A. 发明人 CZARDYBON, WOJCIECH;BRZOZKA, KRZYSZTOF;GALEZOWSKI, MICHAL;WINDAK, RENATA;MILIK, MARIUSZ;ZAWADZKA, MAGDALENA;GUZIK, PAWEL;WINCZA, EWELINA;PROKOP, MARTA;WIKLIK, KATARZYNA;SABINIARZ, ALEKSANDRA;CHOLODY, WIESLAW MAREK;HORVATH, RAYMOND;RZYMSKI, TOMASZ
分类号 C07D235/24;A61K31/4184;A61P29/00;A61P35/00;A61P37/00;C07D235/30;C07D401/04;C07D403/04;C07D403/12;C07D403/14;C07D405/12;C07D413/04;C07D413/12 主分类号 C07D235/24
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