摘要 |
<p>Aminotetralol Compounds Novel aminotetralol compounds of the formula wherein R1 is hydrogen, acyl derived from carboxylic acid, or a hydrocarbon group which may be substituted; -OZ1 is hydroxyl which may be protected; Y is hydrogen, acyl, hydroxyl which may be protected, amino which may be substituted, nitro, cyano or halogen; and n is zero, 1 or 2 with a proviso that when Y is hydrogen or hydroxyl which may be protected, n is not zero, and their salts, have excellent pharmacological activities such as strong bronchodilating activity, They are useful as medicines, for example, for treatment of asthma.</p> |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SUGIHARA, HIROSADA;WATANABE, MASAZUMI;MOTOHASHI, MICHIO;NISHIKAWA, MASAO;SANNO, YASUSHI |