MAMMALIAN APOPTOSIS INHIBITOR PROTEIN GENE FAMILY, PRIMERS, PROBES AND DETECTION METHODS
摘要
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
申请公布号
WO9706255(A2)
申请公布日期
1997.02.20
申请号
WO1996IB01022
申请日期
1996.08.05
申请人
UNIVERSITY OF OTTAWA;KORNELUK, ROBERT, G.;MACKENZIE, ALEXANDER, E.;BAIRD, STEPHEN;LISTON, PETER
发明人
KORNELUK, ROBERT, G.;MACKENZIE, ALEXANDER, E.;BAIRD, STEPHEN;LISTON, PETER