| 发明名称 |
NOVEL CRYSTAL FORM OF ANHYDROUS 7-([1 alpha , 5 alpha , 6 alpha ]-6-AMINO-3-AZABICYCLO[3.1.0]HEX-3-YL)-6-FLUORO-1-(2,4-DIFLUOROPHENYL)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID, METHANESULFONIC ACID SALT |
| 摘要 |
The anhydrate of 7-([1 alpha , 5 alpha , 6 alpha ]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt has advantageous stability for formulation as an antibacterial agent. |
| 申请公布号 |
WO9639406(A1) |
申请公布日期 |
1996.12.12 |
| 申请号 |
WO1995US07211 |
申请日期 |
1995.06.06 |
| 申请人 |
PFIZER INC.;HANDANYAN, LYNNE, A.;MORRIS, THOMAS, A.;HENDRICKSON, ROBERT, L.;JOHNSON, PHILLIP, J.;NORRIS, TIMOTHY |
发明人 |
HANDANYAN, LYNNE, A.;MORRIS, THOMAS, A.;HENDRICKSON, ROBERT, L.;JOHNSON, PHILLIP, J.;NORRIS, TIMOTHY |
| 分类号 |
C07D487/04;A61K;A61K31/00;A61K31/395;A61K31/435;A61K31/4375;A61K31/44;A61K31/495;A61P31/04;C07C303/00;C07C309/00;C07C311/00;C07D;C07D221/00;C07D221/04;C07D471/02;C07D471/04;C07D519/00;(IPC1-7):C07D471/04 |
主分类号 |
C07D487/04 |
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