| 发明名称 |
C7F2-A NOVEL POTASSIUM CHANNEL .BETA.-SUBUNIT |
| 摘要 |
The present invention relates to a newly identified potassium channel .beta. - subunit. The invention also relates to polynucleotides encoding the subunit. The invention further relates to methods using subunit polypeptides and polynucleotides, applicable to diagnosis and treatment in channel-mediated disorders. The invention further relates to drug-screening methods using the polypeptides and polynucleotides to identify agonists and antagonists, applicable to diagnosis and treatment. The invention further encompasses agonists, and antagonists based on the subunit polypeptides and polynucleotides. The invention further relates to procedures for producing t he subunit polypeptides and polynucleotides.
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| 申请公布号 |
CA2335643(A1) |
申请公布日期 |
2000.02.10 |
| 申请号 |
CA19992335643 |
申请日期 |
1999.07.27 |
| 申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
GLUCKSMANN, MARIA ALEXANDRA;CURTIS, RORY |
| 分类号 |
G01N33/50;A61K31/7105;A61K31/711;A61K38/00;A61K45/00;A61K48/00;A61P7/02;A61P9/00;A61P9/06;A61P9/10;A61P9/12;A61P21/00;A61P21/02;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/24;A61P25/28;A61P43/00;C07K14/47;C07K14/705;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/16;C12P21/02;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12N15/12;C12N15/11;C12N15/63;A61K31/70 |
主分类号 |
G01N33/50 |
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