发明名称 Acetamide derivatives
摘要 The invention is concerned with a compound of formula (I); and pharmaceutically acceptable salts thereof wherein R1 to R3, X and Y are as defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
申请公布号 US9359337(B2) 申请公布日期 2016.06.07
申请号 US201514712655 申请日期 2015.05.14
申请人 Hoffmann-La Roche Inc. 发明人 Brotherton-Pleiss Christine E.;Chen Zhi;Erickson Shawn David;Qian Yimin
分类号 C07D211/26;C07D413/04;C07D265/30;C07D207/09 主分类号 C07D211/26
代理机构 代理人 Ackerman Lily J.
主权项 1. A compound of formula (I) wherein: X is —CH2— or oxygen; Y is —(CH2)n—; R1 is phenyl optionally substituted with halogen; R2 is lower alkyl; R3 is trifluoromethyl-phenyl, trifluoromethyl-pyridinyl, trifluoromethyl-pyridazinyl, trifluoromethyl-pyrimidinyl or trifluoromethyl-pyrazinyl; and n is 0 or 1, provided that n is not 0 when X is oxygen; or a pharmaceutically acceptable salt thereof.
地址 Little Falls NJ US