| 摘要 |
A composition for use as a vaccine to protect against Chikungunya virus (CHIKV) infection is disclosed. The composition comprises a nucleic acid comprising a nucleotide sequence encoding an attenuated poxvirus vector and one or more CHIKV structural proteins. In preferred embodiments, the nucleotide sequence encodes all of the C, E3, E2, 6K, and E1 structural proteins. Dosage schedules are also described. |
