This invention relates to certain peptides and linear and cyclic analogs thereof that bind to the mu(morphine) opiate receptor with higher affinity, selectivity and potency than currently available peptides. This invention also relates to pharmaceutical preparations containing an effective amount of the peptides or salts thereof, and methods for providing analgesia, relief from gastrointestinal disorders such as diarrhea, and therapy for drug dependence containing a pharmaceutically effective amount of the peptides.
申请公布号
WO9842732(A1)
申请公布日期
1998.10.01
申请号
WO1998US05719
申请日期
1998.03.24
申请人
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND;ZADINA, JAMES, E.;KASTIN, ABBA, J.;HACKLER, LASZLO