PHOTOCURED CROSS-LINKED-HYALURONIC ACID GEL AND METHOD OF PREPARATION THEREOF

摘要

A photocured cross-linked-hyaluronic acid gel, which has a storage modulus (G') of from 50 to 1500 Pa, a loss modulus (G'') of from 10 to 300 Pa, and a tangent delta (G''/G') of from 0.1 to 0.8 in dynamic viscoelasticity at a frequency of 10 Hz, and which is a hydrogel obtained by irradiation with ultraviolet rays of a photoreactive hyaluronic acid derivative in which a photoreactive cross-linking group is chemically linked to a functional group of the hyaluronic acid and cross-linking of mutual photoreactive cross-linking groups, methods for preparing the same, and uses thereof as biomedical materials.