发明名称 |
Activators of cyclin-dependent kinases |
摘要 |
A new gene family involved in cell cycle regulation was discovered. This family has been termed activators of cyclin-dependent kinases (ACDKs). A number of ACDK genes have been cloned and sequenced. Proteins encoded by ACDK genes specifically were shown to interact with CDKs and pRb, and to upregulate the kinase activity of a CDK using pRb as a substrate. Progression of a cell through the cell cycle can be regulated by modulating ACDK expression in the cell.
|
申请公布号 |
US7033816(B1) |
申请公布日期 |
2006.04.25 |
申请号 |
US20020199229 |
申请日期 |
2002.07.19 |
申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
SHE JIN-XIONG;WANG CONG-YI;KUMAR PRADEEP G. |
分类号 |
C12N15/12;C07H21/04;C12N1/20 |
主分类号 |
C12N15/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|