发明名称 derivados de tetrahidroquinolina usados como ativadores de ampk
摘要 The present invention relates to compounds according to formula (I) and pharmaceutically acceptable salts or esters thereof, wherein R1 to R7 have the significance given herein. The compounds are activators of AMP-activated protein kinase (AMPK) and are useful in the treatment or prophylaxis of diseases that are related to AMPK regulation, such as obesity, dyslipidemia, hyperglycemia, type 1 or type 2 diabetes and cancers.
申请公布号 BR112013009640(A2) 申请公布日期 2016.07.12
申请号 BR20131109640 申请日期 2011.10.17
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GUOLONG WU;LICHUN FENG;MENGWEI HUANG;MINGWEI ZHOU;YONGFU LIU
分类号 A61K31/47;A61P3/02;A61P3/06;A61P3/10;A61P35/00;C07D215/12;C07D215/18;C07D215/48;C07D401/12 主分类号 A61K31/47
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