发明名称 FLUORESCENT COMPOUND RESPONSIVE TO MITOCHONDRIAL MEMBRANE POTENTIAL
摘要 PROBLEM TO BE SOLVED: To provide a dye compound that can stein cells, has a water solubility, has a good light emission efficiency, and has a characteristic of transferring the localization location from mitochondria to nucleus depending on the mitochondrial membrane potential.SOLUTION: Provided are: a compound represented by the following formula (1); a fluorescent dye composition containing said compound; a method for detecting change in mitochondrial membrane potential by using said compound; and a method for discriminating life or death of cells by using said compound. (Ris methyl or the like; Z is halogen or the like; X is naphthylene, anthracene-diyl, pyrene-diyl or the like; X and a pyridine ring may be bonded via ethene-1,2-diyl.)SELECTED DRAWING: None
申请公布号 JP2016166154(A) 申请公布日期 2016.09.15
申请号 JP20150047426 申请日期 2015.03.10
申请人 YAMAGUCHI UNIV;OSAKA SHINYAKU KK 发明人 KAWAMATA JUN;SUZUKI YASUTAKA;MORITOMO HIROKI;FUJIKI SHOHEI
分类号 C07D213/38;C09B6/00;C09B57/00;C09B67/44;G01N21/64 主分类号 C07D213/38
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