发明名称 |
PROCEDIMIENTO PARA LA OBTENCION DE UNA VACUNA ACTIVA CONTRALA ENFERMEDAD DE MARET. |
摘要 |
<p>Marek's disease virus which causes a serious infection in poultry may be attenuated by serial passage in tissue culture. Passaging causes the loss of the A antigen after a certain number of passes while important protective antigens are retained. The virus may be attenuated in avian cells particularly those of the chick and duck, kidney cells and embryo fibroblasts being especially preferred. Usually about 20 to 40 passes are required. The live protective virus so obtained is cultivated further into a vaccine for parenteral administration.</p> |
申请公布号 |
ES373631(A1) |
申请公布日期 |
1972.05.16 |
申请号 |
ES19310003736 |
申请日期 |
1969.11.18 |
申请人 |
NATIONAL RESEARCH DEVELOPMENT CORPORATION |
发明人 |
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分类号 |
C12N7/00;A61K39/255;(IPC1-7):12K/;61K/ |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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