| 摘要 |
A novel process for the preparation of 2-substituted 5chloroimidazole-4-carbaldehydes of the general formula: (see fig. I) (I) wherein R denotes hydrogen, alkyl, alkenyl, cycloalkyl, arylalkyl or aryl, in which glycine is reacted with an imido ester of the general formula: (see fig. II) (II) wherein R is as above and R1 is alkyl, and the resulting intermediate is converted into the target product by a Vilsmeier reagent. The 2-substituted 5-chloroimidazole-4-carbaldehydes (I) are valuable intermediates in the preparation of pharmaceuticals or of herbicidally active compounds.
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