| 发明名称 |
Dual action inhibitors |
| 摘要 |
<p>Compounds of the formula <CHEM> are disclosed as possessing inhibotory activity against angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) and thus being useful as cardiovascular agents. Processes for preparing these compounds are also disclosed.</p> |
| 申请公布号 |
EP0783002(A2) |
申请公布日期 |
1997.07.09 |
| 申请号 |
EP19970200315 |
申请日期 |
1993.05.18 |
| 申请人 |
E.R. SQUIBB & SONS, INC. |
发明人 |
KARANEWSKY, DONALD S.;PETRILLO, EDWARD, W. JR.;RYONO, DENIS E.;BARRISH, JOEL C.;ROBL, JEFFREY A. |
| 分类号 |
A61K31/54;C07D223/24;A61K31/395;A61K31/4353;A61K31/55;A61K31/551;A61K31/553;A61K31/554;A61K38/00;A61K38/55;A61P1/16;A61P9/04;A61P9/12;A61P13/12;A61P43/00;C07D211/76;C07D223/10;C07D223/12;C07D223/16;C07D225/02;C07D225/06;C07D233/16;C07D243/02;C07D243/08;C07D267/08;C07D267/14;C07D279/00;C07D279/06;C07D281/00;C07D281/02;C07D281/04;C07D281/06;C07D281/10;C07D281/18;C07D283/00;C07D283/02;C07D285/36;C07D313/04;C07D313/08;C07D403/12;C07D455/02;C07D471/04;C07D487/02;C07D487/04;C07D498/04;C07D513/02;C07D513/04;C07K1/113;C07K5/06;C07K5/078;C07K14/81;(IPC1-7):C07K1/00 |
主分类号 |
A61K31/54 |
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