| 摘要 |
<p>NEW MATERIAL:A compound expressed by formula I [A is O or S; R<2> is halogenophenyl; R<2> and R<3> are lower alkyl or mutually linked at the terminals to form -(CH2)n- (n is 4-6)]. EXAMPLE:trans-(E)-6-[2-(4-(4-Fluorophenyl)-2,2-diethyl-2H-chromen-3-yl )-1- ethenyl]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-1-one. USE:An antilipemic agent. PREPARATION:A compound (salt) expressed by formula II [-COOR<4> is (protected) carboxyl] is reduced and the protecting group, as desired, is removed. Esterification, amidation and lactonization, as necessary, are then carried out.</p> |
