发明名称 PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED DIAMINOPURINE
摘要 PROBLEM TO BE SOLVED: To provide compounds for use, such as in the prevention or treatment of cancer, inflammatory disorders, autoimmune disorders, immune disorders, metabolic disorders, and fibrotic disorders, as a kinase pathway inhibitor, and further in reducing the risk of contacting with teratogenic agents.SOLUTION: The invention relates to pharmaceutical formulations containing 4-((9-((3S)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9H-purine-2-yl)amino)-trans-cyclohexanol represented by the left formula of the following formulas, or a pharmaceutically acceptable salt, solvate, isotopologue thereof or a tautomer represented by the right formula, and microcrystalline cellulose silicified with the compound. The formulations are capsules or coated tablets.SELECTED DRAWING: None
申请公布号 JP2016155854(A) 申请公布日期 2016.09.01
申请号 JP20160088076 申请日期 2016.04.26
申请人 SIGNAL PHARMACEUTICALS LLC 发明人 SREENIVAS S BHAT;LIANG XIAOZHONG;ANTHONY TUTINO
分类号 A61K31/52;A61K9/30;A61K9/48;A61K47/12;A61K47/26;A61K47/38;A61P1/04;A61P1/16;A61P3/00;A61P3/04;A61P3/10;A61P5/14;A61P9/00;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P19/02;A61P21/04;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08 主分类号 A61K31/52
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