| 摘要 |
A 2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-1-carboxamide of the formula: thereof, WHEREIN R1 is alkenyl of three to eight carbon atoms, inclusive, cycloalkyl of three to six carbon atoms, inclusive, and haloalkyl, in which the alkyl group is of two to six carbon atoms, inclusive and the halogen is fluorine, chlorine, bromine, or iodine; wherein R2, R3, R4, and R5 are selected from the group consisting of hydrogen, alkyl of one to three carbon atoms, inclusive, fluorine, chlorine, bromine, cyano and trifluoromethyl, and wherein R6 is hydrogen or alkyl of one to three carbon atoms, inclusive, and the pharmacologically acceptable acid addition salts thereof, are prepared by reacting a compound of the structure WHEREIN R2, R3, R4, R5, and R6 have the values of above, with an alkenyl, cycloalyl, or haloalkyl isocyanate. The products of formula II are useful as tranquilizers and sedatives. |
