发明名称 |
Bentsotiofeeniyhdisteiden ja vesiliukoisten syklodekstriinien inkluusiokompleksien vesipitoinen liuos ja niiden farmaseuttiset formulaatiot sekä menetelmä |
摘要 |
The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.
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申请公布号 |
FI945839(A) |
申请公布日期 |
1995.06.15 |
申请号 |
FI19940005839 |
申请日期 |
1994.12.12 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
BRYANT, HENRY UHLMAN;CULLINAN, GEORGE JOSEPH;FRANCIS, PAUL CLIFTON;MAGEE, DAVID EDWARD;SWEETANA, STEPHANIE ANN;THAKKAR, ARVIND LAVJI |
分类号 |
C07D333/56;A61K9/08;A61K31/365;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/4535;A61K31/55;A61K47/40;A61K47/48;A61P3/06;A61P7/00;A61P19/08;A61P19/10;A61P43/00;C08B37/16;(IPC1-7):A61K31/38;C08L5/16 |
主分类号 |
C07D333/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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