发明名称 Bentsotiofeeniyhdisteiden ja vesiliukoisten syklodekstriinien inkluusiokompleksien vesipitoinen liuos ja niiden farmaseuttiset formulaatiot sekä menetelmä
摘要 The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.
申请公布号 FI945839(A) 申请公布日期 1995.06.15
申请号 FI19940005839 申请日期 1994.12.12
申请人 ELI LILLY AND COMPANY 发明人 BRYANT, HENRY UHLMAN;CULLINAN, GEORGE JOSEPH;FRANCIS, PAUL CLIFTON;MAGEE, DAVID EDWARD;SWEETANA, STEPHANIE ANN;THAKKAR, ARVIND LAVJI
分类号 C07D333/56;A61K9/08;A61K31/365;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/4535;A61K31/55;A61K47/40;A61K47/48;A61P3/06;A61P7/00;A61P19/08;A61P19/10;A61P43/00;C08B37/16;(IPC1-7):A61K31/38;C08L5/16 主分类号 C07D333/56
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