发明名称 |
Device for generating freely definable libraries of elements in the form of ligand and acceptor structures for combinatorial synthesis, for example in active ingredient research |
摘要 |
The invention relates to a device for generating freely definable libraries of elements (8; 34; 54) in the form of ligand and acceptor structures for combinatorial synthesis, for example in active ingredient research. Said elements are regularly arranged on a substrate (6; 30; 50) along a first and a second coordinate (10; 36; 54 or 12; 38; 58) and a dosing head (14; 42) comes into contact with each element separately and in a controlled manner. In each position the dosing head places a metered quantity of a reagent or solvent onto a corresponding element. The substrate (6; 30; 50) is configured as a rotating body which can be turned about its axis of rotational symmetry (2; 32; 52), which serves as its axis of rotation, in the direction of the first coordinate (10; 36; 54). At least one dosing head (14; 42) can be displaced in relation to the substrate along the second coordinate (12; 38; 58) and parallel to the surface of the substrate, and can be controlled in accordance with its momentary position so as to release a defined quantity of the relevant reagent or solvent. |
申请公布号 |
AU4135799(A) |
申请公布日期 |
1999.11.16 |
申请号 |
AU19990041357 |
申请日期 |
1999.04.26 |
申请人 |
GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) |
发明人 |
RONALD FRANK;NORBERT ZANDER;YVONNE MELBERG;FRANK ADLER;KLAUS ZINECKER;VOLKER THOMAE |
分类号 |
B01J19/00;C07B61/00;C40B40/06;C40B40/10;C40B40/12;C40B60/14 |
主分类号 |
B01J19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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