| 发明名称 |
Hücre-disi sinyal ayarli kinazlarin(ERK) inhibitörü olarak yararli pirazol bilesimler |
| 摘要 |
Burada tanimlanan, (I) numarali formüle sahip preotein kinaz inhibitörleri olarak yararli bilesiklerdir; burada R1-4, Q ve T patentte açiklanmistir. Bu bilesikler memelilerde, protein kinaz inhibitörleri ile kolaylastirilan kanser, ilitihabi hastaliklar, restenoz ve kardiyovasküler hastaliklar gibi hastaliklarin tedavisinde yararlidirlar.
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| 申请公布号 |
TR200103787(T1) |
申请公布日期 |
2002.10.21 |
| 申请号 |
TR20010003787T |
申请日期 |
2001.02.05 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
JEREMY GREEN;JINGRONG CAO;MICHAEL HALE;CHRISTOPHER BAKER;FRANCOIS MALTAIS;JAMES JANETKA;MICHAEL MULLICAN;GUY BEMIS;XIAOLING XIE;JUDITH STRAUB;QUING TANG;ROBERT MASHALL |
| 分类号 |
A61B17/00;A61F2/02;A61K31/4155;A61K31/4178;A61K31/433;A61K31/437;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61K31/551;A61K45/00;A61L27/00;A61P1/00;A61P1/16;A61P1/18;A61P3/10;A61P5/00;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P13/00;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P19/00;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D231/38;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D417/14;C07D471/04;(IPC1-7):C07D403/00 |
主分类号 |
A61B17/00 |
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