发明名称 DIASTEREOMER SALTS OF (±)-ALPHA-(DIFLUOROMETHYL)ORNITHINE-MONOHYDROCHLORIDE MONOHYDRATE AND METHOD OF SEPARATION OF (+)- ALPHA-(DIFLUOROMETHYL)ORNITHINE
摘要 (±)-alpha-(Difluoromethyl)-ornithine is separate into its isomers using (-)-O,O'-di-p-toluoyl-L-tartaric acid. (-)-alpha-(Difluoromethyl)-ornithine monohydrochloride monohydrate and in particular the (-)-isomer are inhibitors of ornithine decarboxylase and thereby have numerous pharmacological actions.
申请公布号 PL195164(B1) 申请公布日期 2007.08.31
申请号 PL19990346900 申请日期 1999.09.22
申请人 LONZA AG 发明人 MEUL THOMAS
分类号 C07C227/34;C07B57/00;C07C69/76;C07C229/26 主分类号 C07C227/34
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