发明名称 PROCESS FOR PREPARING 1,4:3,6-DIANHYDRO-D-GLUCITOL 2-NITRATE
摘要 The following process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate is described: acylating 1,4:3,6-dianhydro-D-glucitol with 0.5 to 1.5 molar equivalents of acetic anhydride in the presence of an acid catalyst, nitrating the product so obtained with a mixture of nitric acid and acetic anhydride, hydrolyzing the product so obtained in the presence of an inorganic base and isolating 1,4:3,6-dianhydro-D-glucitol 2-nitrate. The 1,4:3,6-dianhydro-D-glucitol 2-nitrate is useful as a coronary vasodilator.
申请公布号 ZA7705920(B) 申请公布日期 1978.05.30
申请号 ZA19770005920 申请日期 1977.10.04
申请人 AMERICAN HOME PROD CORP 发明人 CHOU C;MYERS G
分类号 C07D493/04 主分类号 C07D493/04
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