摘要 |
<p>NEW MATERIAL:A compound expressed by the formula [R<1> is (protected) OH; R<2> is H or (protected) OH; R<3> is methyl, ethyl,,propyl or allyl; (n) is 1 or 2; the symbol of solid line and dotted line indicates single or double bond]. EXAMPLE:17-Allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3methoxycyclohexyl)-1- methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4- azatricyclo[23.3.1.0<4>,<9>]octacos-18-ene2,3,10,16-tetraone. USE:An immunosuppressive and antimicrobial agent. PREPARATION:A stain, such as Streptomyces tsukubaensis No.9993 (FERM P-7886), belonging to the genus Streptomyces and capable of producing a substance FR-900506 is cultured in a culture medium.</p> |