| 发明名称 |
CD6 LIGAND |
| 摘要 |
The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for their ability to inhibit that interaction. The invention also relates to antibodies, and binding fragments thereof, specific for CD6 ligand.
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| 申请公布号 |
CA2232142(A1) |
申请公布日期 |
1998.01.29 |
| 申请号 |
CA19972232142 |
申请日期 |
1997.07.17 |
| 申请人 |
DUKE UNIVERSITY;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PATEL, DHAVALKUMAR;BOWEN, MICHAEL A.;MARQUARDT, HANS;ARUFFO, ALEJANDRO;SIADAK, ANTHONY W.;HAYNES, BARTON F. |
| 分类号 |
G01N33/53;A61K31/00;A61K38/00;A61K39/395;A61K45/00;A61P37/00;A61P37/02;C07K14/47;C07K14/705;C07K16/28;C12N5/00;C12N5/10;C12N15/02;C12P21/08;C12R1/91;G01N33/566;G01N33/577;G01N33/68;(IPC1-7):C12N5/18 |
主分类号 |
G01N33/53 |
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