摘要 |
The invention relates to an oil-in-water emulsion comprising, as an active ingredient, alpha -tocopherol or the stereoisomers thereof and comprising, as an emulsifier, phospholipids. The inventive emulsion is used in order to attain a protective action against damages to human organs resulting from peroxidation. The emulsion contains a alpha -tocopherol content, with regard to action, of 1.48 g/l to 30 g/l RRR-g(a)-tocopherol, 0-25 g/l of an oil which is compatible with I.V. administration, and 0.25 g/l to 3 g/l of a phospholipid. The emulsion is preferably administered as an infusion and is especially used to reduce damages resulting from peroxidation due to ischaemia and/or reperfusion and, among other things, during an organ transplantation.
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申请人 |
FRESENIUS KABI AUSTRIA GMBH;EGGENREICH, UDO;FEICHTINGER, NORBERT;HOFER, GERALD;SCHAUPP, KARIN;SOMMERMEYER, KLAUS;WURM, ANNELIESE;NAGEL, ECKHARD;MEYER ZU VILSENDORF, ANDREAS |
发明人 |
EGGENREICH, UDO;FEICHTINGER, NORBERT;HOFER, GERALD;SCHAUPP, KARIN;SOMMERMEYER, KLAUS;WURM, ANNELIESE;NAGEL, ECKHARD;MEYER ZU VILSENDORF, ANDREAS |