发明名称 |
3,4,5-trisubstituted aryl nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation |
摘要 |
Disclosed are 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have the formula:where R1-R4 are as defined in the specification. The disclosed compositions are useful as therapeutics for inflammation-related conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals.
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申请公布号 |
US6342523(B1) |
申请公布日期 |
2002.01.29 |
申请号 |
US19990452529 |
申请日期 |
1999.12.01 |
申请人 |
CENTAUR PHARMACEUTICALS, INC. |
发明人 |
WATERBURY L. DAVID;WILCOX ALLAN L.;CARNEY JOHN M.;MAVANDADI FARAH;DANIELZADEH ALBERT |
分类号 |
A61P19/02;A61K;A61K31/135;A61K31/15;A61K31/235;A61K31/325;A61P19/00;A61P25/00;A61P29/00;A61P37/00;C07C;C07C291/02;C07C323/47;(IPC1-7):A61K31/24;C07C205/00;C07C269/00;C07C291/00 |
主分类号 |
A61P19/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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