发明名称 |
DIAGNOSTIC METHOD AND APPARATUS FOR DETECTING A PREDISPOSITION TO CERTAIN DISEASE STATES, ESPECIALLY OSTEOPOROSIS, BASED ON POLYMORPHISM IN AN IL-6 GENE |
摘要 |
The present invention provides methods of diagnosis of certain disease states, such as osteoporosis, that are associated with polymorphisms in an IL-6 gene, comprising determining the genotype of an IL-6 gene. The invention is also directed to methods of identifying an individual predisposed or susceptible to certain disease states, such as osteoporosis, associated with polymorphisms of an IL-6 gene, comprising determining the genotype of an IL-6 gene in the affected individual. The invention is further directed to compositions useful for determining the genotype of an IL-6 gene, to kits and diagnostic apparatuses comprising such compositions, and to methods of treatment of diseases associated with IL-6 genetic polymorphisms. |
申请公布号 |
WO9743446(A3) |
申请公布日期 |
1998.01.08 |
申请号 |
WO1997GB01337 |
申请日期 |
1997.05.16 |
申请人 |
GEMINI INTERNATIONAL HOLDINGS LIMITED;RALSTON, STUART, HAMILTON;GRANT, STRUAN, FREDERICK, AIRTH |
发明人 |
RALSTON, STUART, HAMILTON;GRANT, STRUAN, FREDERICK, AIRTH |
分类号 |
C12N15/09;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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