发明名称 |
PYRIDINONE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USE |
摘要 |
The present invention is directed to the compound of formula (I), which is 5-[1-(1,3-dimethoxypropan-2-yl)-5-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-1,3-dimethyl-1,2-dihydropyridin-2-one or a salt thereof, in particular pharmaceutically acceptable salts thereof. The compound of formula (I) has been identified as a BET inhibitor and thus has potential for use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis; and cancers. |
申请公布号 |
WO2016139292(A1) |
申请公布日期 |
2016.09.09 |
申请号 |
WO2016EP54516 |
申请日期 |
2016.03.03 |
申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED |
发明人 |
BROWN, John, Alexander;HUMPHREYS, Philip, G;JONES, Katherine, Louise;WELLAWAY, Christopher, Roland |
分类号 |
C07D401/14;A61K31/5377;A61P29/00;A61P37/00 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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