发明名称 PYRIDINONE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USE
摘要 The present invention is directed to the compound of formula (I), which is 5-[1-(1,3-dimethoxypropan-2-yl)-5-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-1,3-dimethyl-1,2-dihydropyridin-2-one or a salt thereof, in particular pharmaceutically acceptable salts thereof. The compound of formula (I) has been identified as a BET inhibitor and thus has potential for use in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis; and cancers.
申请公布号 WO2016139292(A1) 申请公布日期 2016.09.09
申请号 WO2016EP54516 申请日期 2016.03.03
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED 发明人 BROWN, John, Alexander;HUMPHREYS, Philip, G;JONES, Katherine, Louise;WELLAWAY, Christopher, Roland
分类号 C07D401/14;A61K31/5377;A61P29/00;A61P37/00 主分类号 C07D401/14
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