| 摘要 |
<p>1,200,902. Iron-dextran complex. FISONS PHARMACEUTICALS Ltd. 29 April, 1968 [13 May, 1967], No. 22280/67. Heading C3U. [Also in Division A5] A complex of Fe(OH) 3 and dextran is made by slowly adding alkali to an aqueous solution of at least one water-soluble ferric salt at 20-40‹ C. at a rate such as to convert 10-90% of the salt to colloidal Fe(OH) 3 in not less than 30 minutes, subsequently adding an aqueous solution of dextran (as defined) and adjusting the pH to 4-7 followed by heating at 50‹ C. or above for a period sufficient to form a stable complex. The dextran is defined as being hydrogenated, oxidized, alkali treated according to Specification 1,199,951, or partially depolymerized. Examples describe the treatment of FeCl 3 solution with Na 2 CO 3 , followed by addition of a solution of partially-depolymerized, bromine-oxidized dextran and heating at 80‹ C. or autoclaving. The product is useful therapeutically.</p> |
