发明名称 Radioactive labeling of proteins with nucleosides or nucleotides
摘要 A radioactively labeled protein comprising a protein, and a radioactive nucleoside or nucleotide, the protein being covalently linked to the nucleoside or nucleotide. Advantageously the linkage is through an NH2 group of the protein and through a carbonyl group of a ring-opened sugar moiety of the nucleoside or nucleotide. The protein can be insulin, an immunoglobulin or protein A. The radioactive moiety may be a P, C, S, H, I or Hg atom. The labels can be used to indicate the presence and amount of the protein in a biological assay.
申请公布号 US4692509(A) 申请公布日期 1987.09.08
申请号 US19840675373 申请日期 1984.11.27
申请人 MOLECULAR DIAGNOSTICS, INC. 发明人 DATTAGUPTA, NANIBHUSHAN
分类号 C12Q1/68;G01N33/534;G01N33/564;(IPC1-7):A61K43/00;A61N5/12 主分类号 C12Q1/68
代理机构 代理人
主权项
地址