IMPROVED NUCLEIC ACIDS FOR REDUCING CARBOHYDRATE EPITOPES
摘要
The invention relates to nucleic acids which encode a first glycosyltransferase which competes with a second enzyme for a substrate, thereby reducing the formation of a product of the second enzyme. The nucleic acids are useful in producing cells and organs with reduced antigenicity and which may be used for transplantation.
申请公布号
WO9807837(A1)
申请公布日期
1998.02.26
申请号
WO1997AU00540
申请日期
1997.08.22
申请人
THE AUSTIN RESEARCH INSTITUTE;SANDRIN, MAURO, SERGIO;MCKENZIE, IAN, FARQUHAR, CAMPBELL