METHIONINE, PENICILLAMINE AND CYSTEINE-ANALOGUE CONTAINING PEPTIDES HAVING IMMUNOMODULATING ACTIVITY

摘要

Physiologically active peptides of 8ormula (I): A-R1-R2-R3-(R4)x-B, wherein each variable has the meaning mentioned in the description at least one of R1, R2 and R3 being R8 and at most one of R1, R2 and R3 being cysteine; and R8 is an amino acid residue of formula (II) or formula (III), wherein each variable has the meaning described in the description, the entire peptide sequence containing 3 to 30 amino acid residues; or a homo- or heterodimers thereof. These peptides are absorbable by the epithelial cell lining in a mammal resulting in a modulated immune response and thereby a therapeutic effect against disease.