RECOMBINANT ADENOVIRUSES, USE THEREOF FOR PREPARING AAVS, COMPLEMENTARY CELL LINE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID ADENOVIRUSES.

摘要

A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruses for preparing AAVs, and a complementary cell line and preparation method therefor, are also disclosed. Furthermore, pharmaceutical compositions containing such an adenovirus are disclosed.