| 摘要 |
<p>The present invention provides processes for preparing compounds of formula I <CHEM> wherein R<1> is -H, OH, or OR<3>, in which R<3> is a hydroxy protecting group; and R<2> is -H, -OH, or OR<4>, in which R<4> is a hydroxy protecting group, and for preparing compounds of formula VII <CHEM> wherein R<1> is -H, -OH, or OR<3>, in which R<3> is a hydroxy protecting group; R<2> is -H, -OH, or OR<4>, in which R<4> is a hydroxy protecting group; R<5> is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; R<6> is bromo, chloro, iodo, or an activating ester group; and n is 2 or 3. Also provided are processes for preparing compounds of formula VII in addition to intermediates of formula IX <CHEM> wherein R<1'> is -OH, or -OR<3>, in which R<3> is a hydroxy protecting group; and Z is bromo, iodo, triflate, or -B(OH)2.or p</p> |
