POLYESTERS CONTAINING ALKYLENE OXIDE BLOCKS AS DRUG DELIVERY SYSTEMS

摘要

A diblock copolymer is disclosed having a first block of a polyalkylene oxide and a second block of glycolic acid ester and trimethylene carbonate linkages. A triblock copolymer is disclosed having a middle block obtained from an ethylene oxide homopolymer or a copolymer of ethylene oxide and a cyclic ether. Alternatively, the triblock copolymer middle block is obtained from a copolymer of formula (I): (I) and formula (II): (II) The copolymers are useful in medical and surgical applications.