| 摘要 |
NEW MATERIAL:An antibiotic substance SF2543 having the following characteristics and salts thereof. Color and shape; yellow crystal. Molecular formula; C20H16O5S. Mass spectrum (FD-MS); m/Z368(M<+>). Melting point; 227-228 deg.C (decomposition). Specific rotatory power; [alpha] =-157 deg. (C=0.1, CHCl3- CH3OH=1:1). Solubility; soluble in chloroform, ethyl acetate and acetone, sparingly soluble in methanol and insoluble in water. Weak acidic substance, etc. USE:An antitreponemal agent, antianaerobic bacterial agent and material for conversion thereinto. PREPARATION:A microorganism, belonging to the genus Streptomyces and capable of producing the antibiotic substance SF2543 [e.g., Streptomyces sp. SF2543 (FERM P-10291)] is cultured at about 28 deg.C under aerobic conditions for 2-7 days by a submerged culture method. |
