PEPTIDE DERIVATIVES, COMPOSITIONS AND USES IN THERAPEUTIC TREATMENT OF HERPESVIRUS INFECTION

摘要

The invention concerns novel peptide derivatives derived from lactoferrin, antibodies and pharmaceutical compositions comprising same as well as kits and methods for screening active molecules, in particular molecules having an activity in the treatment of herpesvirus-mediated infections. The invention also concerns genetic constructs, cells and compositions useful for implementing such screening methods, for example genetically modified cells for overexpressing part of the lactoferrin, as well as methods for preparing said cells. The invention can be implemented for identifying active compounds or compounds useful as lead compounds for developing active medicines for treating pathologies mediated by a viral infection.