发明名称 |
Aerosol drug inhibition of lung metastases |
摘要 |
The present invention provides a method of inhibiting growth of lung metastases in an individual comprising the steps of administering a dose of a lipid-drug enhancer liposomal complex and, in sequence, administering a dose of a lipid-anticancer drug liposomal complex. Furthermore, the lipid-drug enhancer liposomal complex may be administered in a continuing dose with the lipid-anticancer drug liposomal complex whereby both liposomal complexes are mixed in the nebulizer. Methods of inhibiting growth of lung metastases in an individual by the sequential administration via aerosolization of a dilauroylphosphatidylcholine-cyclosporin A liposomal complex and a dilauroylphosphatidylcholine-paclitaxel liposomal complex are also provided.
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申请公布号 |
US7288243(B2) |
申请公布日期 |
2007.10.30 |
申请号 |
US20030439773 |
申请日期 |
2003.05.16 |
申请人 |
RESEARCH DEVELOPMENT FOUNDATION |
发明人 |
KNIGHT J. VERNON;WALDREP J. CLIFFORD;KOSHKINA NADEZHDA |
分类号 |
A61K47/00;A61K9/00;A61K9/127;A61K31/337;A61K31/4745;A61K31/704;A61K31/7048;A61K38/13;A61K47/30 |
主分类号 |
A61K47/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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